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Naica System for Crystal Digital PCR 3-color digital PCR in 2 hours TM


The Naica System leverages the key assets of Crystal Digital PCR in a compact, easy-to-use, fast and reliable digital PCR solution.

What is the Naica System ? See our brochures

A single consumable per experiment


Two instruments for the entire workflow

Digital PCR results in under 2 hours, including thermocycling


Less than 5 min hands-on time

A unique 3-color detection


User-friendly analysis software

An easy-to-use and integrated solution The fastest time-to-result on the market Reliable multiplex digital PCR

Crystal Digital PCR is Stilla’s next-generation technology for absolute quantification of nucleic acids.


Using cutting-edge microfluidic innovations, this technology integrates the digital PCR process in a single consumable. The sample is first flowed through a network of microchannels and partitioned into a large 2D array of 25,000 to 30,000 individual droplets, also called a droplet crystal. PCR is then performed on-chip and the crystal is imaged to reveal the droplets that contain amplified targets. The last step consists in counting the number of these positive droplets to precisely extract the absolute quantity of nucleic acids.


With Crystal Digital PCR, the combination of powerful image analysis and intuitive visual inspection offers an unmatched level of confidence in the digital PCR measurement, yielding data you can truly trust.

Crystal Digital PCR
A simple and fast Workflow 1
Generate crystals & Amplify


Load the reaction mixes into the wells of the Sapphire chips


Place the chips into the Naica Geode


Launch the Crystal Digital PCR program



Crystals of 25,000 to 30,000 droplets are created from each sample


PCR amplification is performed immediately after crystal generation

A simple and fast Workflow
Read & Analyze


Transfer the chips to the Naica Prism3 crystal reader





Measure the concentrations of targeted nucleic acids with Crystal Miner software

Crystals are read using 3 fluorescent channels


Rémi Dangla , PhD CEO Clément Gay, HEC Paris CFO Magali Droniou , PhD Applications Director Etienne Fradet, PhD Director of product management


US Stilla Technologies

Villejuif Biopark


1, Mail du Professeur Georges Mathé, 94800 Villejuif, FRANCE




Tel : (+33) 09 82 29 50 50